Ser409

Site Information
VITARRPsVsENLYP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 23071314

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 , 3 )
Disease tissue studied:	lung cancer ( 2 ) , mesothelioma ( 2 ) , non-small cell lung cancer ( 2 ) , non-small cell lung cancer, surrounding tissue ( 3 ) , non-small cell squamous cell lung carcinoma ( 2 )
Relevant cell line - cell type - tissue:	lung ( 3 ) , NCI-H226 (pulmonary) ( 2 )

Upstream Regulation
Kinases, in vitro:	PKG1 (human) ( 1 )

References
1	Wang GR, et al. (2013) Steroid-sensitive Gene 1 Is a Novel Cyclic GMP-dependent Protein Kinase I Substrate in Vascular Smooth Muscle Cells. J Biol Chem 288, 24972-83 23831687 Curated Info
2	Rikova K (2011) CST Curation Set: 10904; Year: 2011; Biosample/Treatment: cell line, NCI-H226/untreated; Disease: non-small cell squamous cell lung carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[STY]) Curated Info
3	Rikova K (2008) CST Curation Set: 5354; Year: 2008; Biosample/Treatment: tissue, lung/untreated; Disease: non-small cell lung cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info