Ser437
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Home > Phosphorylation Site Page: > Ser437  -  IRF5 (human)

Site Information
FSGELsWsADsIRLQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455994

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:
2fTGH (fibroblast) ( 2 ) , E.coli (bacterial) ( 1 )

Downstream Regulation
Effects of modification on IRF5:
activity, induced ( 1 )
Effects of modification on biological processes:
transcription, induced ( 2 )

References 

1

Chen W, et al. (2008) Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5. Nat Struct Mol Biol 15, 1213-20
18836453   Curated Info

2

Barnes BJ, Kellum MJ, Field AE, Pitha PM (2002) Multiple regulatory domains of IRF-5 control activation, cellular localization, and induction of chemokines that mediate recruitment of T lymphocytes. Mol Cell Biol 22, 5721-40
12138184   Curated Info