Ser390

Site Information
PDSEASQsPQYsFES SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 11273301

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 ) , mammary gland ( 1 ) , MCF10A1 (epithelial) ( 1 )

Downstream Regulation
Effects of modification on PR iso2:	protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:	apoptosis, induced ( 1 ) , carcinogenesis, altered ( 1 ) , cell growth, inhibited ( 1 )

References
1	Wang S, et al. (2013) Progesterone receptor A stability is mediated by glycogen synthase kinase-3β in the Brca1-deficient mammary gland. J Biol Chem 288, 26265-74 23880761 Curated Info