Thr675
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Thr675  -  Ret (human)

Site Information
PISSAEMtFRRPAQA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 22553316

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 )
Treatments:
chelerythrine ( 1 ) , colforsin ( 1 ) , depolarization ( 1 ) , H-89 ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on Ret:
intracellular localization ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )

References 

1

Li XZ, et al. (2012) Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion. J Biol Chem 287, 1932-45
22128160   Curated Info