Ser863
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Home > Phosphorylation Site Page: > Ser863  -  GluR2 (rat)

Site Information
NPSSSQNsQNFATyk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455806

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 3 ) , mass spectrometry ( 1 ) , mutation of modification site ( 3 ) , phospho-antibody ( 2 , 3 ) , phosphoamino acid analysis ( 3 ) , phosphopeptide mapping ( 3 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
'brain, hippocampus' ( 2 ) , 'neuron, cortical'-brain ( 3 ) , 293 (epithelial) ( 3 ) , brain ( 1 )

Upstream Regulation
Regulatory protein:
RAP2A (human) ( 2 )
Putative in vivo kinases:
PKCA (rat) ( 3 )
Kinases, in vitro:
PKCA (rat) ( 3 )
Treatments:
phorbol_ester ( 3 )

References 

1

Guo A (2007) CST Curation Set: 2239; Year: 2007; Biosample/Treatment: tissue, brain/ischemia 20'; Disease: -; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: p[ST]Q Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Ser/Thr) ATM/ATR Substrate Antibody Cat#: 2851
Curated Info

2

Zhu Y, et al. (2005) Rap2-JNK removes synaptic AMPA receptors during depotentiation. Neuron 46, 905-16
15953419   Curated Info

3

McDonald BJ, Chung HJ, Huganir RL (2001) Identification of protein kinase C phosphorylation sites within the AMPA receptor GluR2 subunit. Neuropharmacology 41, 672-9
11640921   Curated Info