Ser128

Site Information
VRsFLKRsKLGRyNE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455785

In vivo Characterization
Methods used to characterize site in vivo:	[32P] bio-synthetic labeling ( 1 , 2 ) , mutation of modification site ( 1 , 2 )
Disease tissue studied:	breast cancer ( 1 , 2 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 ) , IMR-90 (fibroblast) ( 2 ) , MCF-7 (breast cell) ( 2 ) , ZR-75-1 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	cytoskeletal reorganization ( 1 , 2 )

References
1	Rayala SK, et al. (2007) Dynamic interplay between nitration and phosphorylation of tubulin cofactor B in the control of microtubule dynamics. Proc Natl Acad Sci U S A 104, 19470-5 18048340 Curated Info
2	Vadlamudi RK, et al. (2005) p21-activated kinase 1 regulates microtubule dynamics by phosphorylating tubulin cofactor B. Mol Cell Biol 25, 3726-36 15831477 Curated Info