Ser425
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser425  -  SMAD3 (rat)

Site Information
SIRCSsVs_______   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448336

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) ( 1 ) , R22 ('muscle, smooth') ( 1 ) , SYF (fibroblast) ( 1 ) , vascular smooth muscle cell ('muscle, smooth') ( 1 )

Upstream Regulation
Treatments:
TGF-beta ( 1 ) , Y27632 ( 1 )

References 

1

Samarakoon R, Higgins SP, Higgins CE, Higgins PJ (2008) TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling. J Mol Cell Cardiol 44, 527-38
18255094   Curated Info