Thr178
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Home > Phosphorylation Site Page: > Thr178  -  JNK1 (human)

Site Information
GLARTAGtsFMMtPy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2192624

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 ) , phospho-antibody ( 3 ) , western blotting ( 3 )
Disease tissue studied:
lymphoma ( 3 ) , B cell lymphoma ( 3 ) , Burkitt's lymphoma ( 3 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 3 ) , B lymphocyte ( 3 ) , BJAB (B lymphocyte) ( 3 ) , Jurkat (T lymphocyte) ( 2 ) , K562 (erythroid) ( 1 ) , Raji (B lymphocyte) ( 3 ) , WEHI-231 (B lymphocyte) ( 3 )

Upstream Regulation
Regulatory protein:
APC (human) ( 3 ) , ARHGEF4 (mouse) ( 3 ) , KHS1 (human) ( 3 )
Treatments:
sFRP-1 ( 3 ) , Wnt3a ( 3 )

References 

1

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

2

Wissing J, et al. (2007) Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry. Mol Cell Proteomics 6, 537-47
17192257   Curated Info

3

Shi CS, et al. (2006) The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes. Mol Cell Biol 26, 6511-21
16914735   Curated Info