Ser721
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Home > Phosphorylation Site Page: > Ser721  -  ERK5 (mouse)

Site Information
DPLPPVFsGtPKGSG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455519

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 3 ) , mass spectrometry ( 2 ) , mutation of modification site ( 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 3 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 )

References 

1

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

2

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

3

Morimoto H, et al. (2007) Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation. J Biol Chem 282, 35449-56
17928297   Curated Info