Ser171

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Home > Phosphorylation Site Page: > Ser171 - HPK1 (mouse)

Site Information
ATLARRLsFIGTPYW SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455474

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	lymphoma ( 1 ) , T cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:	Jurkat (T lymphocyte) ( 1 ) , S49 (T lymphocyte) ( 1 )

Upstream Regulation
Putative in vivo kinases:	PKACA (mouse) ( 1 )
Treatments:	H-89 ( 1 ) , PGE2 ( 1 )

Downstream Regulation
Effects of modification on HPK1:	enzymatic activity, induced ( 1 )

References
1	Sawasdikosol S, et al. (2007) Prostaglandin E2 activates HPK1 kinase activity via a PKA-dependent pathway. J Biol Chem 282, 34693-9 17895239 Curated Info

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