Tyr1387
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Home > Phosphorylation Site Page: > Tyr1387  -  NMDAR2A (human)

Site Information
GRCPSDPyKHSLPSQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 455471

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 )
Disease tissue studied:
CSWSS ( 1 ) , Status epilepticus ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , blood ( 1 )

Downstream Regulation
Effects of modification on NMDAR2A:
activity, induced ( 2 )

Disease / Diagnostics Relevance
Relevant diseases:
CSWSS ( 1 ) , Status epilepticus ( 1 )

References 

1

Lesca G, et al. (2013) GRIN2A mutations in acquired epileptic aphasia and related childhood focal epilepsies and encephalopathies with speech and language dysfunction. Nat Genet 45, 1061-6
23933820   Curated Info

2

Zheng F, Gingrich MB, Traynelis SF, Conn PJ (1998) Tyrosine kinase potentiates NMDA receptor currents by reducing tonic zinc inhibition. Nat Neurosci 1, 185-91
10195142   Curated Info