Lys824

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Home > Ubiquitylation Site Page: > Lys824 - MALT1 (human)

Site Information
DRLRISEk_______ SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 2134710

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Disease tissue studied:	leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 1 ) , T lymphocyte-lymph node ( 1 ) , T lymphocyte-spleen ( 1 )

Downstream Regulation
Effects of modification on MALT1:	molecular association, regulation ( 1 ) , protein degradation ( 1 )
Induce interaction with:	IKKA (human) ( 1 )

References
1	Oeckinghaus A, et al. (2007) Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation. EMBO J 26, 4634-45 17948050 Curated Info

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