Ser164

Site Information
REGTRVQsVEQIREV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 2089803

In vivo Characterization
Methods used to characterize site in vivo:	[32P] ATP in vitro ( 2 ) , immunoprecipitation ( 2 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Disease tissue studied:	luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, surrounding tissue ( 1 ) , breast cancer, triple negative ( 1 )
Relevant cell line - cell type - tissue:	breast ( 1 ) , NCI-H295R ( 2 )

Upstream Regulation
Kinases, in vitro:	PAK6 (human) ( 2 ) , PKACA (human) ( 2 )

References
1	Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62 27251275 Curated Info
2	Dammer EB, Sewer MB (2008) Phosphorylation of CtBP1 by cAMP-dependent protein kinase modulates induction of CYP17 by stimulating partnering of CtBP1 and 2. J Biol Chem 283, 6925-34 18184656 Curated Info