Tyr274

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Home > Phosphorylation Site Page: > Tyr274 - MAIR-I (mouse)

Site Information
LPQEELHySSVAFNS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 455227

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:	RBL-2H3 (basophil) ( 1 )

Upstream Regulation
Treatments:	vanadate ( 1 )

Downstream Regulation
Effects of modification on MAIR-I:	molecular association, regulation ( 1 )
Induce interaction with:	SHIP (mouse) ( 1 ) , SHP-1 (mouse) ( 1 ) , SHP-2 (mouse) ( 1 )

References
1	Okoshi Y, et al. (2005) Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3. Int Immunol 17, 65-72 15569773 Curated Info

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