Ser50
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Home > Phosphorylation Site Page: > Ser50  -  CDC25B (human)

Site Information
PVRAAASsPVttLtQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 20503402

In vivo Characterization
Methods used to characterize site in vivo:
[32P] ATP in vitro ( 2 ) , mass spectrometry ( 1 , 3 ) , mass spectrometry (in vitro) ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CDK1 (human) ( 2 ) , PLK1 (human) ( 2 )

Downstream Regulation
Effects of modification on CDC25B:
phosphorylation ( 2 )

References 

1

Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7
23749302   Curated Info

2

Lobjois V, et al. (2011) Study of the docking-dependent PLK1 phosphorylation of the CDC25B phosphatase. Biochem Biophys Res Commun 410, 87-90
21640712   Curated Info

3

Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5
21712546   Curated Info