Lys79

Site Information
REIAQDFktDLrFQs SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18545333

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 )
Relevant cell line - cell type - tissue:	HCT116 (intestinal) ( 1 , 4 ) , HEK293T (epithelial) ( 3 ) , HeLa S3 (cervical) ( 2 ) , Jurkat (T lymphocyte) ( 5 )

Downstream Regulation
Effects of modification on H3F3A:	molecular association, regulation ( 3 )
Induce interaction with:	L3MBTL iso4 (human) ( 3 )

References
1	Guo A, et al. (2014) Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics 13, 372-87 24129315 Curated Info
2	Bremang M, et al. (2013) Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome. Mol Biosyst 9, 2231-47 23748837 Curated Info
3	Moore KE, et al. (2013) A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation. Mol Cell 50, 444-56 23583077 Curated Info
4	Mulhern D (2011) CST Curation Set: 13061; Year: 2011; Biosample/Treatment: cell line, HCT116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m2K Curated Info
5	Possemato A (2008) CST Curation Set: 5337; Year: 2008; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m2K Curated Info