Ser630
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.6.0.2
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser630  -  HDAC4 (rat)

Site Information
RPLSRAQsSPASATF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448490

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 ) , mutation of modification site ( 1 )
Disease tissue studied:
bone cancer ( 1 )
Relevant cell line - cell type - tissue:
stomach ( 2 ) , UMR106 (bone cell) ( 1 )

Upstream Regulation
Treatments:
H-89 ( 1 ) , okadaic_acid ( 1 ) , PTH ( 1 )

Downstream Regulation
Effects of modification on HDAC4:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Inhibit interaction with:
AML3 (rat) ( 1 )

References 

1

Shimizu E, Nakatani T, He Z, Partridge NC (2014) Parathyroid Hormone Regulates Histone Deacetylase (HDAC) 4 through Protein Kinase A-mediated Phosphorylation and Dephosphorylation in Osteoblastic Cells. J Biol Chem 289, 21340-50
24904057   Curated Info

2

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info