Tyr377

Site Information
LCAESMLyHCMSDSE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18899303

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	cell differentiation, altered ( 1 ) , signaling pathway regulation ( 1 )

References
1	Quintanar-Audelo M, et al. (2011) Sprouty-related Ena/Vasodilator-stimulated Phosphoprotein Homology 1-Domain-containing Protein (SPRED1), a Tyrosine-Protein Phosphatase Non-receptor Type 11 (SHP2) Substrate in the Ras/Extracellular Signal-regulated Kinase (ERK) Pathway. J Biol Chem 286, 23102-12 21531714 Curated Info