Lys213

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Home > Ubiquitylation Site Page: > Lys213 - CTLA-4 (human)

Site Information
PTEPECEkQFQPyFI SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1887094204

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , western blotting ( 1 )
Disease tissue studied:	melanoma skin cancer ( 1 )
Relevant cell line - cell type - tissue:	A2058 (keratinocyte) ( 1 ) , HeLa S3 Flp-In ( 1 ) , T lymphocyte-spleen ( 1 )

Downstream Regulation
Effects of modification on CTLA-4:	enzymatic activity, induced ( 1 ) , protein degradation ( 1 )

References
1	Tey PY, et al. (2024) Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation. bioRxiv 38260548 Curated Info

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