Lys419

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Home > Ubiquitylation Site Page: > Lys419 - GATA2 (human)

Site Information
ECFEELSkCMQEkSS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1883354002

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	prostate cancer ( 1 )
Relevant cell line - cell type - tissue:	22Rv1 (prostate cell) ( 1 ) , C4-2B (prostate cell) ( 1 ) , LNCaP (prostate cell) ( 1 )

Downstream Regulation
Effects of modification on biological processes:	cell growth, inhibited ( 1 )

References
1	Shen T, et al. (2022) A COP1-GATA2 axis suppresses AR signaling and prostate cancer. Proc Natl Acad Sci U S A 119, e2205350119 36251994 Curated Info

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