Arg57

Site Information
ELKHAHHrPQAQPAP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1881305500

In vivo Characterization
Methods used to characterize site in vivo:	flow cytometry ( 1 ) , immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	breast cancer ( 1 ) , breast ductal carcinoma ( 1 ) , breast cancer, triple negative ( 1 )
Relevant cell line - cell type - tissue:	HCC1806 (breast cell) ( 1 ) , HCC1937 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on KLF5:	protein stabilization ( 1 )
Effects of modification on biological processes:	cell growth, induced ( 1 )

References
1	Wang X, et al. (2021) Arginine methyltransferase PRMT5 methylates and stabilizes KLF5 via decreasing its phosphorylation and ubiquitination to promote basal-like breast cancer. Cell Death Differ 28, 2931-2945 33972717 Curated Info