Thr57
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Home > Phosphorylation Site Page: > Thr57  -  myogenin (mouse)

Site Information
LEEKGLGtPEHCPGQ   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1880114102

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'muscle, skeletal' ( 1 ) , A293T ('renal, embryonic') ( 1 ) , C2C12 (myoblast) ( 1 ) , myotubes ( 1 )

Upstream Regulation
Putative in vivo kinases:
PDHK4 (human) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on myogenin:
molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Induce interaction with:
FBXO32 (human) ( 1 )

References 

1

Sinam IS, et al. (2022) Pyruvate dehydrogenase kinase 4 promotes ubiquitin-proteasome system-dependent muscle atrophy. J Cachexia Sarcopenia Muscle
36259412   Curated Info

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