Thr362
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Home > Phosphorylation Site Page: > Thr362  -  HOXA10 (human)

Site Information
FLFNMyLtRERRLEI   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1880104200

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
endometrial cancer ( 1 ) , endometrial adenocarcinoma ( 1 ) , urethral cancer ( 1 )
Relevant cell line - cell type - tissue:
BeWo ( 1 ) , HEK293T (epithelial) ( 1 ) , Ishikawa (endometrial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
MEKK4 (human) ( 1 )
Kinases, in vitro:
MEKK4 (human) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on HOXA10:
protein stabilization ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, induced ( 1 )

References 

1

Zhang M, et al. (2022) MEKK4-mediated Phosphorylation of HOXA10 at Threonine 362 facilitates embryo adhesion to the endometrial epithelium. Cell Death Discov 8, 415
36216824   Curated Info

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