Arg637

Site Information
AGMVLGGrKFKKFNK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1876957800

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , microscopy-colocalization with upstream kinase ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	T47D (breast cell) ( 1 )

Downstream Regulation
Effects of modification on PR:	protein degradation ( 1 ) , receptor recycling, induced ( 1 )
Effects of modification on biological processes:	cell growth, induced ( 1 ) , cell motility, induced ( 1 ) , transcription, induced ( 1 )

References
1	Malbeteau L, et al. (2020) PRMT1 Is Critical for the Transcriptional Activity and the Stability of the Progesterone Receptor. iScience 23, 101236 32563156 Curated Info