Ser62
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Home > Phosphorylation Site Page: > Ser62  -  CDK8 (mouse)

Site Information
EGTGISMsACREIAL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1876860402

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , mononuclear-blood ( 1 )

Upstream Regulation
Putative in vivo kinases:
LATS1 (human) ( 1 )
Kinases, in vitro:
LATS1 (human) ( 1 )
Treatments:
IFN-alpha ( 1 ) , IFN-beta ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on CDK8:
phosphorylation ( 1 )
Effects of modification on biological processes:
cell growth, inhibited ( 1 ) , transcription, induced ( 1 )

References 

1

Zuo Y, et al. (2022) LATS1 is a central signal transmitter for achieving full type-I interferon activity. Sci Adv 8, eabj3887
35394840   Curated Info

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