Lys49

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Home > Ubiquitylation Site Page: > Lys49 - CENPA (human)

Site Information
rRRQGWLkEIRKLQK SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1876695602

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 1 )

Downstream Regulation
Effects of modification on CENPA:	intracellular localization ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:	cell cycle regulation ( 1 )

References
1	Wang K, et al. (2021) Phosphorylation at Ser68 facilitates DCAF11-mediated ubiquitination and degradation of CENP-A during the cell cycle. Cell Rep 37, 109987 34758320 Curated Info

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