Ser581

Javascript is not enabled on this browser. This site will not work properly without Javascript.

Home > Phosphorylation Site Page: > Ser581 - HIF2A (human)

Site Information
LAPVAPHsPFLLDKF SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1874020206

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , HeLa (cervical) ( 2 )

Downstream Regulation
Effects of modification on biological processes:	transcription, altered ( 2 )

References
1	Zhang A, et al. (2022) USP33 deubiquitinates and stabilizes HIF-2alpha to promote hypoxia response in glioma stem cells. EMBO J 41, e109187 35191554 Curated Info
2	Daly LA, et al. (2021) Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α. Sci Signal 14 34285132 Curated Info

Developed with grants from

and literature mining with Linguamatics

PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.