Ser115
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Home > Phosphorylation Site Page: > Ser115  -  MAPKAPK5 (mouse)

Site Information
GELFHRIsQHRHFTE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18704700

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 )

Upstream Regulation
Regulatory protein:
PKACA (mouse) ( 1 )

Downstream Regulation
Effects of modification on MAPKAPK5:
intracellular localization ( 1 ) , molecular association, regulation ( 1 ) , protein stabilization ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 ) , transcription, induced ( 1 )
Induce interaction with:
ERK3 (human) ( 1 )

References 

1

El-Merahbi R, et al. (2020) The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation. Genes Dev 34, 495-510
32139423   Curated Info