Ser115
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Home > Phosphorylation Site Page: > Ser115  -  MAPKAPK5 (human)

Site Information
GELFHRIsQHRHFTE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18704700

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
adrenal cancer ( 1 ) , pheochromocytoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
PKACA (human) ( 1 )
Treatments:
colforsin ( 1 )

Downstream Regulation
Effects of modification on MAPKAPK5:
intracellular localization ( 1 )
Effects of modification on biological processes:
cytoskeletal reorganization ( 1 )

References 

1

Kostenko S, et al. (2011) Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function. Cell Mol Life Sci 68, 847-62
20734105   Curated Info