Ser126
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Home > Phosphorylation Site Page: > Ser126  -  CAPZA1 (human)

Site Information
SWREsCDsALRAYVk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1870026100

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mass spectrometry (in vitro) ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
prostate cancer ( 1 )
Relevant cell line - cell type - tissue:
DU 145 (prostate cell) ( 1 ) , LNCaP (prostate cell) ( 1 ) , PC3 (prostate cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Pim1 (human) ( 1 )
Kinases, in vitro:
Pim1 (human) ( 1 )
Treatments:
AZD1208 ( 1 ) , SGI-1776 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
cell adhesion, induced ( 1 ) , cell motility, induced ( 1 ) , cytoskeletal reorganization ( 1 )

References 

1

Santio NM, et al. (2020) PIM1 accelerates prostate cancer cell motility by phosphorylating actin capping proteins. Cell Commun Signal 18, 121
32771000   Curated Info

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