Ser262

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Home > Phosphorylation Site Page: > Ser262 - HCRTR1 (human)

Site Information
VRNWKRPsDQLGDLE SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1869999600

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 )

Downstream Regulation
Effects of modification on HCRTR1:	molecular association, regulation ( 1 ) , receptor internalization, induced ( 1 )
Effects of modification on biological processes:	endocytosis, induced ( 1 )
Induce interaction with:	AP-2 alpha (human) ( 1 ) , GRK2 (human) ( 1 )

References
1	Cai X, et al. (2020) A novel phosphorylation site on orexin receptor 1 regulating orexinA-induced GRK2-biased signaling. Cell Signal 75, 109743 32827691 Curated Info

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