Lys536

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Home > Ubiquitylation Site Page: > Lys536 - Nur77 (human)

Site Information
NRIASCLkEHVAAVA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 1869841400

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	breast cancer ( 1 )
Relevant cell line - cell type - tissue:	breast ( 1 ) , MCF-7 (breast cell) ( 1 )

Downstream Regulation
Effects of modification on Nur77:	protein degradation ( 1 )

References
1	Yang PB, et al. (2020) Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proc Natl Acad Sci U S A 117, 27412-27422 33087562 Curated Info

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