Ser561
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Home > Phosphorylation Site Page: > Ser561  -  SCN8A (human)

Site Information
PFLSRHNsKSSIFSF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1869659200

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phosphopeptide mapping ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , ND7/23 ('neuron, dorsal root ganglion') ( 1 )

Upstream Regulation
Putative in vivo kinases:
CAMK2A (human) ( 1 )
Treatments:
KN-92 ( 1 ) , KN-93 ( 1 )

Downstream Regulation
Effects of modification on SCN8A:
activity, induced ( 1 )
Effects of modification on biological processes:
neural plasticity ( 1 )

References 

1

Zybura AS, et al. (2020) CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. J Biol Chem
32611770   Curated Info