Ser256
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.1.1
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser256  -  NFAT2 (human)

Site Information
EsWLGARssRPAsPC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1869090802

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
prostate cancer ( 1 )
Relevant cell line - cell type - tissue:
DU 145 (prostate cell) ( 1 ) , LNCaP (prostate cell) ( 1 ) , PC3 (prostate cell) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Pim1 (human) ( 1 )

Downstream Regulation
Effects of modification on NFAT2:
activity, induced ( 1 )
Effects of modification on biological processes:
carcinogenesis, induced ( 1 ) , cell motility, induced ( 1 ) , transcription, induced ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
prostate cancer ( 1 )

References 

1

Eerola SK, et al. (2019) Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion. Cell Commun Signal 17, 148
31730483   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2019 Cell Signaling Technology, Inc.