Thr101
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Home > Phosphorylation Site Page: > Thr101  -  SCN5A (human)

Site Information
IVLNKGKtIFRFSAT   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 1867858201

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , myocyte ( 1 )

Upstream Regulation
Putative in vivo kinases:
AMPKA1 (human) ( 1 )
Kinases, in vitro:
AMPKA1 (human) ( 1 )
Treatments:
A-769662 ( 1 ) , glucose_starvation ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on SCN5A:
molecular association, regulation ( 1 ) , protein degradation ( 1 )
Effects of modification on biological processes:
autophagy, induced ( 1 ) , endocytosis, altered ( 1 )
Induce interaction with:
LC3B (human) ( 1 )

References 

1

Liu X, et al. (2019) AMPK-mediated degradation of Nav1.5 through autophagy. FASEB J 33, 5366-5376
30759345   Curated Info