Ser79
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Home > Phosphorylation Site Page: > Ser79  -  JunB (human)

Site Information
QGSDTGAsLKLASSE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454237

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 2 ) , phospho-antibody ( 1 )
Disease tissue studied:
lung cancer ( 1 ) , non-small cell lung cancer ( 1 )
Relevant cell line - cell type - tissue:
MC3T3-E1 (preosteoblast) [JunB (mouse)] ( 2 ) , MC3T3-E1 (preosteoblast) [p300 (human)] ( 2 ) , NCI-H460 (pulmonary) ( 1 )

Upstream Regulation
Treatments:
2-deoxyglucose ( 1 ) , SB203580 ( 2 )

Downstream Regulation
Effects of modification on JunB:
activity, induced ( 2 )
Effects of modification on biological processes:
transcription, altered ( 2 )
Induce interaction with:
p300 (human) ( 2 )

References 

1

Zhong D, et al. (2009) The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R. J Biol Chem 284, 23225-33
19574224   Curated Info

2

Narayanan K, et al. (2004) Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation. J Biol Chem 279, 44294-302
15308641   Curated Info

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