Ser356

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Home > Phosphorylation Site Page: > Ser356 - NRF2 (human)

Site Information
NTsPSVAsPEHSVES SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 18258502

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )

Downstream Regulation
Effects of modification on NRF2:	molecular association, regulation ( 2 ) , protein degradation ( 1 )
Inhibit interaction with:	BTRC (human) ( 2 )

References
1	Miller WP, et al. (2020) The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation. J Biol Chem 295 32295843 Curated Info
2	Rada P, et al. (2012) Structural and Functional Characterization of Nrf2 Degradation by the Glycogen Synthase Kinase 3/β-TrCP Axis. Mol Cell Biol 32, 3486-99 22751928 Curated Info

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