Ser1033
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Home > Phosphorylation Site Page: > Ser1033  -  INSR (human)

Site Information
LRELGQGsFGMVyEG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454090

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 , 2 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 2 ) , liver ( 1 )

Upstream Regulation
Regulatory protein:
PKCB iso2 (human) ( 2 ) , PKCH (human) ( 2 )

Downstream Regulation
Effects of modification on INSR:
phosphorylation ( 2 )

References 

1

Coba MP, Turyn D, Peña C (2003) Synthesis and immunogenic properties of phosphopeptides related to the human insulin receptor. J Pept Res 61, 17-23
12472845   Curated Info

2

Strack V, et al. (2000) Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta. Diabetologia 43, 443-9
10819237   Curated Info

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