Ser51
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser51  -  DYNC1I2 (mouse)

Site Information
AVSVQEEsDLEKKRR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18260536

In vivo Characterization
Methods used to characterize site in vivo:
electrophoretic mobility shift ( 1 ) , mass spectrometry ( 2 , 4 , 5 ) , mutation of modification site ( 1 )
Disease tissue studied:
melanoma skin cancer ( 5 )
Relevant cell line - cell type - tissue:
'brain, cerebral cortex' ( 1 ) , 'neuron, cortical'-brain ( 1 ) , 293 (epithelial) ( 1 ) , COS7 (fibroblast) ( 1 ) , liver ( 2 , 4 ) , liver [leptin (mouse), homozygous knockout] ( 4 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 5 )

References 

1

Naito Y, Asada N, Nguyen MD, Sanada K (2020) AMP-activated protein kinase regulates cytoplasmic dynein behavior and contributes to neuronal migration in the developing neocortex. Development
32554528   Curated Info

2

Robles MS, Humphrey SJ, Mann M (2017) Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology. Cell Metab 25, 118-127
27818261   Curated Info

3

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

4

Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83
23140645   Curated Info

5

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info