Ser355
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Home > Phosphorylation Site Page: > Ser355  -  NRF2 (mouse)

Site Information
PEHsVESsIYGDPPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 18258504

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
GSK3B (mouse) ( 1 )
Kinases, in vitro:
GSK3B (mouse) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on NRF2:
molecular association, regulation ( 1 ) , protein degradation ( 1 )
Induce interaction with:
BTRC (mouse) ( 1 )

References 

1

Rada P, et al. (2011) SCF/{beta}-TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner. Mol Cell Biol 31, 1121-33
21245377   Curated Info

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