Ser359
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Home > Phosphorylation Site Page: > Ser359  -  GPR15 (human)

Site Information
RRRKRsVsL______   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 17737600

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 , 2 ) , mutation of modification site ( 2 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on GPR15:
intracellular localization ( 2 ) , molecular association, regulation ( 2 ) , protein processing ( 2 )
Induce interaction with:
14-3-3 beta (human) ( 2 )
Inhibit interaction with:
COPB1 (human) ( 2 )

References 

1

Okamoto Y, Shikano S (2017) Differential phosphorylation signals control endocytosis of GPR15. Mol Biol Cell 28, 2267-2281
28615320   Curated Info

2

Okamoto Y, Shikano S (2011) Phosphorylation-dependent C-terminal Binding of 14-3-3 Proteins Promotes Cell Surface Expression of HIV Co-receptor GPR15. J Biol Chem 286, 7171-81
21189250   Curated Info