Tyr508
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Home > Phosphorylation Site Page: > Tyr508  -  SH3PXD2B (human)

Site Information
DMSASAGyEEIsDPD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 17303901

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
colorectal cancer ( 1 ) , colorectal carcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 1 )

Downstream Regulation
Effects of modification on SH3PXD2B:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
carcinogenesis, altered ( 1 ) , cytoskeletal reorganization ( 1 )
Induce interaction with:
NOXA1 (human) ( 1 )

References 

1

Gianni D, Taulet N, DerMardirossian C, Bokoch GM (2010) c-Src-mediated phosphorylation of NoxA1 and Tks4 induces the reactive oxygen species (ROS)-dependent formation of functional invadopodia in human colon cancer cells. Mol Biol Cell 21, 4287-98
20943948   Curated Info