Thr6
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Home > Phosphorylation Site Page: > Thr6  -  UNG (human)

Site Information
__MIGQktLysFFsP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 453426

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry (in vitro) ( 1 ) , phospho-antibody ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative upstream phosphatases:
PPM1D (mouse) ( 2 )
Phosphatases, in vitro:
PPM1D (mouse) ( 2 )
Treatments:
UV ( 2 )

Downstream Regulation
Effects of modification on UNG:
molecular association, regulation ( 1 )
Inhibit interaction with:
PCNA (human) ( 1 )

References 

1

Weiser BP, Stivers JT, Cole PA (2017) Investigation of N-Terminal Phospho-Regulation of Uracil DNA Glycosylase Using Protein Semisynthesis. Biophys J 113, 393-401
28746850   Curated Info

2

Lu X, et al. (2004) The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair. Mol Cell 15, 621-34
15327777   Curated Info