Thr576
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Home > Phosphorylation Site Page: > Thr576  -  HCN2 (human)

Site Information
DYIIREGtIGKKMyF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15785721

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Downstream Regulation
Effects of modification on HCN2:
activity, inhibited ( 1 )
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

References 

1

Norberg E, et al. (2010) Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis. EMBO J 29, 3869-3878
21037554   Curated Info