Ser493
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Home > Phosphorylation Site Page: > Ser493  -  RAP1GAP iso6 (mouse)

Site Information
SRFGRRGsALGIGAV   Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15703808

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 )
Relevant cell line - cell type - tissue:
'brain, striatum' ( 2 ) , 'fat, brown' ( 4 ) , brain ( 4 , 5 ) , kidney ( 4 ) , lung ( 4 ) , MC3T3-E1 (preosteoblast) ( 3 )

Upstream Regulation
Treatments:
PTH(1-34) ( 3 ) , SKF81297 ( 2 )

References 

1

Sacco F, et al. (2016) Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion. Nat Commun 7, 13250
27841257   Curated Info

2

Nagai T, et al. (2016) Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo. Neuron 89, 550-65
26804993   Curated Info

3

Williams GR, et al. (2016) Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics. Methods 92, 36-50
26160508   Curated Info

4

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

5

Wiƛniewski JR, et al. (2010) Brain phosphoproteome obtained by a FASP-based method reveals plasma membrane protein topology. J Proteome Res 9, 3280-9
20415495   Curated Info