Lys40

Site Information
LLIVGDQkFRAHKNV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 15511872

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 3 , 4 )
Relevant cell line - cell type - tissue:	293N3S (epithelial) ( 3 ) , HeLa (cervical) [SUMO2 (human), transfection, SUMO2 K0 Q87R (lysine-deficient SUMO2, with Q87R to create convenient Trypsin cleavage site)] ( 1 ) , HeLa (cervical) [SUMO2 (human), transfection] ( 4 )

References
1	Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36 25218447 Curated Info
2	Impens F, Radoshevich L, Cossart P, Ribet D (2014) Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. Proc Natl Acad Sci U S A 111, 12432-7 25114211 Curated Info
3	Tammsalu T, et al. (2014) Proteome-wide identification of SUMO2 modification sites. Sci Signal 7, rs2 24782567 Curated Info
4	Matic I, et al. (2010) Site-specific identification of SUMO-2 targets in cells reveals an inverted SUMOylation motif and a hydrophobic cluster SUMOylation motif. Mol Cell 39, 641-52 20797634 Curated Info