Ser178

Site Information
TAHNkRIsTLTIEEG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 451282

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	cervical cancer ( 2 ) , cervical adenocarcinoma ( 2 )
Relevant cell line - cell type - tissue:	HeLa (cervical) ( 1 , 3 ) , HeLa S3 (cervical) ( 2 )

Upstream Regulation
Treatments:	BI2536 ( 1 ) , MLN8054 ( 1 ) , nocodazole ( 2 )

References
1	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
2	Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3 20068231 Curated Info
3	Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7 18669648 Curated Info