Ser171
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Home > Phosphorylation Site Page: > Ser171  -  CRYA1 (mouse)

Site Information
FSGPKVQsGLDAGHs   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 452108

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
lens ( 2 , 3 ) , retinal ( 1 )

Downstream Regulation
Effects of modification on biological processes:
apoptosis, inhibited ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
diabetes mellitus ( 1 )

References 

1

Ruebsam A, et al. (2018) A specific phosphorylation regulates the protective role of αA-crystallin in diabetes. JCI Insight 3
29467334   Curated Info

2

Schaefer H, et al. (2006) Study of posttranslational modifications in lenticular alphaA-Crystallin of mice using proteomic analysis techniques. Biochim Biophys Acta 1764, 1948-62
17157567   Curated Info

3

Schaefer H, et al. (2003) Identification of phosphorylation and acetylation sites in alphaA-crystallin of the eye lens ( mus musculus) after two-dimensional gel electrophoresis. Anal Bioanal Chem 376, 966-72
12856102   Curated Info

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