Lys129
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Home > Acetylation Site Page: > Lys129  -  ERR1 (human)

Site Information
EITKRRRkACQACRF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 15211513

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 ) , COS (fibroblast) ( 1 ) , fibroblast-embryo ( 1 ) , Hepa 1-6 (epithelial) ( 1 ) , liver ( 1 )

Upstream Regulation
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on ERR1:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )
Inhibit interaction with:
DNA ( 1 )

References 

1

Wilson BJ, et al. (2010) An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha. Mol Endocrinol 24, 1349-58
20484414   Curated Info

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