Ser787

Site Information
VsKAtsPstLVSTGP SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 15177369

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 )
Disease tissue studied:	neuroblastoma ( 4 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) ( 6 ) , liver ( 2 ) , liver [leptin (mouse), homozygous knockout] ( 2 ) , macrophage-peritoneum ( 1 ) , MEF (fibroblast) [p53 (mouse), homozygous knockout] ( 3 ) , N1E-115 (neuron) ( 4 ) , testis ( 5 )

Upstream Regulation
Treatments:	LPA ( 4 ) , NAG-thiazoline ( 6 ) , okadaic_acid ( 6 ) , PUGNAc ( 6 )

References
1	Wu X, et al. (2012) Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics. Mol Cell Proteomics 11, 1640-51 22942356 Curated Info
2	Grimsrud PA, et al. (2012) A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metab 16, 672-83 23140645 Curated Info
3	Hsu PP, et al. (2011) The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. Science 332, 1317-22 21659604 Curated Info
4	Wang Y, et al. (2011) Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction. J Biol Chem 286, 18190-201 21454597 Curated Info
5	Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89 21183079 Curated Info
6	Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. Proc Natl Acad Sci U S A 105, 13793-8 18779572 Curated Info